first tirzepatide injection How to Adapt During the Month of Use? First Time Taking Tirzepatide: What

Cell Metab (2021) 33(5):104261.e7

As obese subjects appear to display a more rapid gastric emptying of solids compared to normal weight subjects (86) and the natural increase in plasma GLP-1 is attenuated in obese subjects (86, 87), the smaller release of GLP in the obese subjects could cause less pronounced satiety of food intake, leading to earlier onset of the next meal

If possible, the combination of interacting drugs should be avoided

Patients who are already on Zepbound through Aetna may be able to request a continuity exception to avoid disruption, though this is not guaranteed and depends on the specific employer plan

Marks MS, Seabra MC